UNPACKING: POSSIBLE MK-11 SCENARIOS
*POSSIBLE SPOILER ALERT
1. Deadly Alliance retcon
Quan Chi is dead. Assuming his character ending is legit, he's now the Elder Gods' bitch anyway("reprogrammed" to kill the now corrupted Raiden).
2. Deception retcon
IF Reptile's ending is canon, it seems he would be too preoccupied with returning his people to the surface rather than unwittingly stumbling into the Dragon King's lair. Likewise, I have a feeling Cassie's ending is canon as well, considering the whole Dark Raiden turn of events(basically, she killed Shujinko, on the orders of Raiden, thinking it was Shang Tsung. Most likely Raiden commanded it on purpose to ensure the Dragon King won't be ressurected).
3. Expressway to Armageddon
Kenshi and Takeda's ending suggested that they stumbled upon the whole Daegon/Taven scenario.
4. Dark Raiden
Pretty much confirmed with the final cutscene, further supported by Raiden's, Scorpion's and Kotal Khan's individual endings. And I got my answer as to what happens to Hanzo and his Shirai Ryu(Scorpion becomes Raiden's personal "anti-Spectre", if you will).
5. Rulers of Netherrealm
Also confirmed in the final scene, as well as Liu Kang and Kitana's character endings(still don't know whattaheck happened to Jade though). Kung Lao and Kung Jin's character endings would also explain why Kung Lao was absent from the Netherrealm ruling committee.
6. A Death In The Family
Sonya and Jax's endings would suggest that Briggs Sr might not make it to the next game, after trying to save the cubs' lives from an Erron Black ambush.
7. Notable mentions
Kano's son would probably be a new character for the next game. Shang Tsung would make a come back(if Ermac's ending is legit), and possibly have a hand in the events of the next game.

